ABSTRACT

In this study, we report a couple who had been infertility problem for eight years and they had four failed IUI and one failed IVF. In second IVF attempt the women got pregnant and it resulted with abortion in eight week.

Cytogenetic analysis was performed by standart peripheral blood culture and GTG method by using phytohemagglutinin-stimulated lymphocyte.

The women and her husband were phenotypically normal but karyotype analysis revealed 46, XX and 46,XY,t(9;11)(p12;p11.2) respectively. The mother of the husband's karyotype analysis showed the same translocation. The father of the husband's could not examined because he was not alive. Also two uncles of the husband were suffered from infertility for fifteen and five years respectively. However cytogenetic analyses of the uncles had not been accomplished yet. Balanced translocation carriers could give unbalanced chromosomes.

The infertility cases of especially monosomy 9p and the other similar translocations that can result from the parents of balanced translocation carriers are represented here by comparing.