E-ISSN: 2149-9330
The role of midtrimester amniotic fluid leptin and endothelin-1 levels in prediction of preeclampsia
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Clinical Investigation
VOLUME: 9 ISSUE: 1
P: 37-41
March 2012

The role of midtrimester amniotic fluid leptin and endothelin-1 levels in prediction of preeclampsia

Turk J Obstet Gynecol 2012;9(1):37-41
DOI: 10.5505/tjod.2012.42204
Ahmet Tayyar 1
Ahter Tanay Tayyar 1
Ümmühan Abdülrezzak 2
Mustafa Kula 2
Mustafa Taş 1
Mehmet Tayyar 1
1. Department Of Obstetrics And Gynecology,Erciyes University,Kayseri
2. Department Of Nuclear Medicine,Erciyes University,Kayseri
No information available.
No information available
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ABSTRACT

Objective:

We investigated leptin and endothelin-1 levels of amniotic fluid (AF) which was collected during genetic amniocentesis to use these parameters for prediction of preeclampsia.

Meterial and methods:

The level of leptin and endothelin-1 were measured in the samples of AF which were obtained at 16-20 weeks of pregnancy during genetic amniocentesis. We recorded the patients who developed preeclampsia and who had healthy pregnancy and birth.

Results:

AF leptin and endothelin-1 levels were significantly increased in the preeclamptic group compared to control group.

Conclusion:

As we detected increased level of AF leptin and endothelin-1 before preeclampsia symptoms develop we think that these proteins can be used to predict preeclampsia. Thus, early follow up and treatment of preeclampsia could decrease possible complications and related financial expense.