E-ISSN: 2149-9330
Recent Advances in In Vitro Fertilization: Proteomics, Secretomics, Metabolomics and In Vitro Maturation
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Review
VOLUME: 10 ISSUE: 1
P: 1-8
March 2013

Recent Advances in In Vitro Fertilization: Proteomics, Secretomics, Metabolomics and In Vitro Maturation

Turk J Obstet Gynecol 2013;10(1):1-8
DOI: 10.5505/tjod.2013.64497
Ercan Baştu
Gülşah Keskin
Hasan Serdaroğlu
1. Department Of Obstetrics And Gynecology, Istanbul University School Of Medicine, Istanbul, Turkey
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ABSTRACT

Since its first successful result in 1978, clinicians and researchers have been working on increasing the efficiency and safety of in vitro fertilization (IVF). As a result of advances in technology and understanding of human reproduction, IVF success rates have increased while high-order multiple pregnancy (triplets and more) rates have decreased. On the other, there is opportunity for further improvement as many couples still face ‘unexplained infertility’ and high rates of twin pregnancies. Latest technologic and scientific improvements in IVF are promising.

The aim of this review is to present the latest advances in the fields of proteomics, secretomics, metabolomics and oocyte culture, how they can potentially improve embryo selection and in vitro maturation (IVM) and subsequently their possible impact on the safety and efficacy of IVF.