Liver diseases in pregnancy
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Review
VOLUME: 5 ISSUE: 3
P: 166 - 173
September 2008

Liver diseases in pregnancy

Turk J Obstet Gynecol 2008;5(3):166-173
1. Department Of Internal Medicine, Cumhuriyet University, Sivas, Turkey
2. Department Of Obstetrics And Gynecology, Cumhuriyet University, Sivas, Turkey
3. Department Of Internal Medicine, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey
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ABSTRACT

Liver disease in pregnancy is rare and it is associated with the high maternal and neonatal mortality rate. Some of the liver diseases are specific for pregnancy. The most common liver diseases in pregnancy are Acute fatty liver of pregnancy, Intrahepatic cholestasis of pregnancy, HELLP syndrome, liver dysfunction due to preeclampsia, hyperemesis gravidarum, Hepatitis E of pregnancy, and other Hepatitis infections, and Budd-Chiari syndrome. In this review, incidence, risk factors, pathogenesis, clinical presentation, diagnosis, treatment and outcome of those liver diseases unique to pregnancy are discussed through the literature.

Keywords:
Pregnancy, liver disease, Acute fatty liver, Intrahepatic cholestasis, HELLP syndrome, preeclampsia, hyperemesis gravidarum, Hepatitis, Budd-Chiari syndrome