ABSTRACT

Systemic inflammatory response that occurred in foetus called foetal inflammation response syndrome. İt is characterized via existance of fetal vasculitis and increased proinflamatory cytokines in amnion fluid or in fetal blood. There is a intrauterine infection and foetus gives reaction to it. It effects maternal decidua,myometrium, amniotic and chorionic membranes, amnion fluid, umblical cord and placenta. Recent studies claims that these intraamniotic cytokines is originated from foetus. The effect of foetal inflammatory response on probable consequences are more important.

In conclusion it is claimed that the ethiology of mostly seen complications like periventricular leukomalacia, intraventricular hemorrhage in preterm delivery may occur due to perinatal cytokin responce and gives rise to cerebral damage. Furthermore; impaired biophysical profile, depression at labour, asfixia are the clinical findings of this syndrome.