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HISTORY OF CONTRACEPTIVE USE AND AFFECT ON MAMMOGRAPHIC PATTERNS

  • Sitki Gülhan
  • Burcu Dilek
  • Nurdan Barca
  • Saffet Dilek

Turk J Obstet Gynecol 2005;2(4):311-315

OBJECTIVE: To investigate the affect of previous combined oral contraceptives use on mammographic density in the postmenopausal asymptomatic women. Design: Retrospective cross-sectional trial Setting: Tertiary training and education hospital, mammography unit Patients: Study population consisted from 219 women who had history of combined oral contraceptive (COC) use and exposed or group included 200 women had no history of COC. Intervention: Screening mammography Main Outcome Patterns: mammographic breast patterns according to Wolfe Classification RESULTS: Twenty-two percent of exposed (48) and 20 % (40) of unexposed groups had high-risk mammographic pattern. Increased breast density such as P2 and Dy (Wolfe classification) was higher in the exposed group, however this difference was not statistically significant (p=0.66). Odds ratio for having high-risk mammograms of subjects who had previous history of COC’s was 1.14 (95 % CI: 0.62-2.09). Only BMI were related with mammographic density (p=0.01 and Pearson co-efficient= -0.407). CONCLUSIONS: Previous history oral contraceptive use is most likely only making a small and statistically non-significant contribution to mammographic breast density.

Keywords: combined oral contraceptives, mammographic density, menopause, screening mammography, wolfe classification