Clinical Investigation

Evulation of Rh D Alloimmünized Pregnancies Treated with Intrauterine Transfusions and Perinatal Outcomes

  • Yalçın KİMYA
  • Mehmet BÜLBÜL
  • Oktay ALTUN
  • Candan CENGİZ

Turk J Obstet Gynecol 2009;6(3):178-184

OBJECTIVE:

To analyze a data of Rh D alloimmunized pregnancies due to fetal anemia and managed with intrauterine transfusions.And to analyze data of perinatal outcomes.

METHOD:

Between 1994 to 2005 years, 119 transfusions performed for 31 gravid Rh alloimmunized women.And files data retrospectively in a department of obstetrics and gynecology ( Uludağ University Faculty of Medicine) were analyzed.

RESULTS:

Totally 31 RhD immunized pregnant women with complicated fetal anemia were made 119 intrauterine transfusions.13 fetuses were hydropic. While in 9/13(69,2%) of these hydropic fetuses the condition resolved, it persisted in 4/13(30,8%). The fetal survival was 16/18( 88,9%) for nonhydropic, 9/9(100%) for the resolving hydropic, and 2/4(50%) for the persistently hydropic fetuses.

CONCLUSION:

Fetal anemia due to RhD alloimmunization can be managed with intrauterine transfusions until the end of the 35th week of gestation with a good perinatal outcome.

Keywords: Intrauterine transfusion, fetal anemia, RhD alloimmunization