Objective:
To identify prognostic factors which affect the success of ectopic pregnancy treatment with a single dose metotrexate.
Methods:
99 patients whom applied to Cerrahpaşa Medical Faculty Obstetrics and Gynecology Department, between year 2000 and 2010 treated with single-dose methotrexate were divided into two subgroups; successful and unsuccessful. Likely to affect the success of the demographic clinical and laboratory findings were compared retrospectively.
Results:
Single-dose MTX therapy has been successful in 67 patients (% 67.6). In the unsuccessful group, serum ß- hCG values were significantly higher than successful group. (Successful group ß -hCG value: 1180±953 mIU/ml, Unsuccessful group ß- hCG value: 5613±7630 mIU/ml,p: 0,001)
Conclusion:
Single-dose MTX therapy is effective in the initial treatment of ectopic pregnancy. It is observed that the main prognostic factor affecting the success is elevated levels of ß -hCG.
Keywords: Ectopic pregnancy, Single-dose MTX therapy, ß- hCG