Letter to the Editor

Copeptin, the prediction of poor ovarian reserve and the infertile women: Correspondence


  • Rujittika Mungmunpuntipantip
  • Viroj Wiwanitkit

Received Date: 16.12.2022 Accepted Date: 06.01.2023 Turk J Obstet Gynecol 2023;20(1):85-85 PMID: 36908107

Keywords: Copeptin, ovarian, reserve, infertile

Dear Editor,

We wants to share ideas on the publication “A potential marker for predicting poor ovarian reserve (POR) in the infertile women(1).” To determine the association between the level of serum copeptin and the presence of POR in infertile women, Görkem and Yıldırım(1) conducted their research. According to Görkem and Yıldırım(1), this investigation verified that the infertile women with POR had a higher blood copeptin concentration and that copeptin may have a predictive value for developing POR. To elucidate the potential impacts of copeptin in the POR pathogenesis, future large-scale prospective investigations are necessary(1). We both agree that copeptin may be effective for ovarian reserve prediction. But it’s important to be aware of any confounding factors. The interpretation needs to be careful in areas where hemoglobinopathy is prevalent. High levels of copeptin have been linked to thalassemia(2).


Peer-review: Internally peer-reviewed.

Authorship Contributions

Surgical and Medical Practices: R.M., V.W., Concept: R.M., V.W., Design: R.M., V.W., Data Collection or Processing: R.M., V.W., Analysis or Interpretation: R.M., V.W., Literature Search: R.M., V.W., Writing: R.M., V.W.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

  1. Görkem CU, Yıldırım E. opeptin: A potential marker for the prediction of poor ovarian reserve in the ınfertile women. Turk J Obstet Gynecol 2022;19:281-6.
  2. Saadatifar H, Niayeshfar A, Soltani MM, Bahrampour E, Khalili S, Dezfuli DA, et al. The correlation of cardiac biomarkers and myocardial iron overload based on T2* MRI in major beta-thalassemia. Int J Cardiovasc Imaging. 2021 Nov 2. doi: 10.1007/s10554-021-02458-y. Online ahead of print.