Clinical Investigation

‘Sleep Quality Is Related to Hyperinsulinemia In Postmenopausal Women’

10.5505/tjod.2014.10438

  • Nilgün Güdücü
  • Salih Serdar Kutay
  • Uzay Görmüş
  • Başak Özge Kayan
  • İlkkan Dünder

Turk J Obstet Gynecol 2014;11(1):35-41

Objective:

In this study, our aim was to understand the relationship among sleep disturbances and biochemical, hormonal and inflammatory parameters.

Methods:

In this prospective study, 57 postmenopausal women without any concomitant disease other than metabolic syndrome were included. We applied Pittsburgh Sleep Quality Index (PSQI) and asked self-reported sleep duration of participants. We compared the results with hormonal and metabolic parameters.

Results:

Participants with a poor PSQI were older (p=0.022), had a higher hip circumference (p=0.03) and had a longer duration of menopause (p=0.012) when compared to participants with a good PSQI. Participants with a poor PSQI had lower HDL (p=0.008) and higher insulin (p=0.027) when compared to participants with a good PSQI. There was no association between sleep duration and the parameters searched.

Conclusion:

Sleep complaints are related to hyperinsulinemia and lipid abnormalities.

Keywords: sex-hormones, CRP, sleep, postmenopausal, inflammation, insulin