Evidence based approach to recurrent miscarriage


  • Barış Ata
  • Ayşe Seyhan Ata
  • Bulent Urman

Turk J Obstet Gynecol 2011;8(1):5-20

Recurrent miscarriage, defined as three or more consecutive misscarriages, affects approximately 0.5-1% of couples trying to have a child. Genetic and uterine abnormalities, thrombophilias, environmental, endocrinologic and immunologic factors have been proposed to play a role in the etiology of recurrent miscarriage. The underlying pathology remains unidentified in aproximately half of the recurrent miscarriage patients. Couples’ expectations for a treatment often causes physicians to employ empiric treatments. In this review we will discuss the prognosis and evidence-based aproach to diagnosis and treatment of recurrent miscarriage.

Keywords: recurrent pregnancy loss, recurrent miscarriage, spontaneous abortion, early pregnancy loss